People will feel very scared when talking about acne, because acne is very harmful and often has a great impact on people's image. Moreover, the onset of acne is often very sudden, and acne can grow out of fair and tender skin in an instant. Another thing that grows on the surface of the skin is similar to acne, but it doesn’t have much impact. Let’s take a look at what happens when pimples appear on the face but they are not acne? Acne is a chronic inflammatory skin disease of the pilosebaceous unit that mainly occurs in adolescents and has a great psychological and social impact on them, but it often subsides or heals naturally after puberty. The clinical manifestations are characterized by polymorphic skin lesions such as acne, papules, pustules, nodules, etc. that are prone to occur on the face. Causes The occurrence of acne is closely related to factors such as excessive sebum secretion, blockage of the sebaceous gland ducts of the hair follicles, bacterial infection and inflammatory response. After entering puberty, the level of androgens, especially testosterone, in the human body increases rapidly, promoting the development of sebaceous glands and producing a large amount of sebum. At the same time, abnormal keratinization of the sebaceous gland ducts of the hair follicles causes blockage of the ducts, hindering the excretion of sebum and forming keratin plugs, also known as micro-acne. Various microorganisms, especially Propionibacterium acnes, multiply in large numbers in the hair follicles. The lipase produced by Propionibacterium acnes breaks down sebum to produce free fatty acids, while also attracting inflammatory cells and mediators, ultimately inducing and aggravating the inflammatory response. Acne treatment in stages (1) Level 1 is generally treated locally, with topical retinoic acid preparations being the first choice. (2) Level 2: Combined use of topical retinoids and benzoyl peroxide or antibiotics, and oral antibiotics if necessary. (3) Grade 3 often requires combined treatment, with oral antibiotics combined with topical benzoyl peroxide and/or retinoic acid drugs as the first choice. Antiandrogen therapy may also be considered for female patients where indicated. (4) Grade 4 oral isotretinoin is the most effective treatment and can be used as first-line treatment. For patients with more inflammatory papules and pustules, systemic antibiotics combined with topical benzoyl peroxide can be used first, and then oral isotretinoin can be used for sequential treatment after the skin lesions have improved significantly. Maintenance treatment of acne Regardless of the treatment method used, maintenance treatment should be continued after the skin lesions have significantly subsided. Topical retinoic acid drugs are the first choice, and maintenance treatment should be continued for 6 to 12 months. Benzoyl peroxide can be used in combination if necessary. |
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