What causes a low neutrophil ratio?

The level of neutrophil ratio is an important data to determine whether there is inflammation in the human body. However, many friends know that if it is too high, it is caused by bacterial infection, and only bactericidal treatment is needed to recover well. For a low neutrophil ratio, it is more complicated. In order to let you better understand the neutrophil ratio, here we will analyze the reasons for the low neutrophil ratio.

Neutrophils are a type of white blood cell and also a type of immune cell in the body. When there is an inflammatory infection, the body will be stimulated to produce a large number of neutrophils to kill pathogens and fight the inflammatory infection. Reduction is generally seen in infectious diseases such as typhoid, paratyphoid, measles, influenza, chemotherapy, and radiotherapy. Certain blood diseases (plastic anemia, agranulocytosis, myelodysplastic syndrome), hypersplenism, autoimmune diseases, etc.

There are several common reasons for low neutrophil count:

1. Infection, especially bacillus infection. Some viral infections may also be low, such as influenza, viral hepatitis, etc.

2. Blood system diseases, such as aplastic anemia, malignant tumors, etc.

3. Damage caused by physical and chemical factors, such as X-rays, anti-tumor drugs, etc.

4. Hyperfunction of the mononuclear phagocyte system, such as hypersplenism.

5. Autoimmune diseases, such as systemic lupus erythematosus.

The low rate is caused by infection. Recheck blood routine test after infection is under control. It is better to use antibiotics to control the infection. You can do a drug sensitivity test and use targeted medication. The cell membrane of neutrophils can release an unsaturated fatty acid - arachidonic acid, which, under the action of enzymes, further produces a group of paracrine hormone substances, such as thromboxane and prostaglandins. These substances have a significant effect on regulating blood vessel caliber and permeability, can also cause inflammatory reactions and pain, and affect blood coagulation.

After knowing the reasons for the low neutrophil ratio, I hope patients will pay attention. Although there are many reasons for the low neutrophil ratio, it is relatively easy to treat as long as the root cause is found and relevant treatment is carried out. Generally, after treatment, the patient's neutrophil ratio will quickly return to the normal range.