What is the best way to treat acne?

Acne represents youth, but also means that our appearance is affected. Many people often get acne. After getting acne, you can use the antibiotic tetracycline for treatment. You can also choose to take it internally or topically to achieve the treatment effect.

The course of acne fluctuates greatly, so the treatment varies greatly. First of all, patients should be told to pay attention to their eating habits, eat less spicy, oily foods and sweets, eat more fresh vegetables and fruits, and adjust the function of the digestive tract. Wash the affected area with warm water and soap, avoiding squeezing with your hands.

The purpose of acne treatment is: ① to correct the changes in the keratinization pattern of hair follicles; ② to reduce the activity of sebaceous glands; ③ to reduce the flora of hair follicles, especially PA; ④ to reduce the inflammatory response.

1. Oral therapy

(1) Antibiotics: Oral administration of tetracycline, erythromycin, roxithromycin, minocycline (minocycline), etc. can significantly reduce the concentration of free fatty acids in sebum, inhibit Propionibacterium acnes and its chemotactic activity on leukocytes.

①Tetracycline: 0.5-1g/d, reduce the dose according to the therapeutic response, and the maintenance dose is 0.25g per day. Effective for moderate and severe papulopustular acne. Oral erythromycin can irritate the gastrointestinal tract, so it is generally not recommended. Clindamycin (Clindamycin) and clindamycin (Clindamycin) were commonly used in the past, but they may cause pseudomembranous colitis, so they are rarely used in recent years.

② Doxycycline (deoxytetracycline, doxycycline): This drug is more effective than tetracycline. Resistance rarely occurs. The first dose is 0.2g, followed by 0.1-0.2g/time, once a day. However, this drug is prone to photosensitivity and should not be taken in summer.

③ Minocycline (minocycline, minocycline): It has a better effect on the regression of papules and pustules in patients with acne, and is also effective for cystic acne. 50 mg/time, 2 times/d, with side effects such as dizziness, headache and gastrointestinal discomfort. Occasionally, autoimmune hepatitis and lupus erythematosus-like syndrome may occur after taking this drug.

In addition, oxytetracycline, chlortetracycline and sulfonamides (trimethoprim plus sulfamethoxazole) can be used as appropriate. Penicillin and neomycin are almost ineffective and should not be used. Antibiotics are not required for grade I treatment.